Wu Lab

wu_lab

About

Our lab's research is focused on the development and translation of new technologies for Quantitative MRI-Guided Therapy, which includes detection/characterization, treatment planning, interventional guidance, and treatment monitoring of cancer and metabolic diseases.

Research Directions and Specific Projects

Quantitative Prostate MRI

  • Quantitative T2 and ADC mapping in prostate cancer
  • High-resolution diffusion-weighted MRI
  • Microstructural MRI
  • Integrated diagnostics for prostate cancer (collaboration with Urology and Pathology)

Quantitative Liver and Abdominal MRI

  • Free-breathing quantitative MRI of liver fat fraction and R2*
  • MRI and MRE of pediatric liver disease (collaboration with Pediatrics)
  • Artificial intelligence for body composition analysis

Quantitative Placenta MRI

  • Free-breathing quantitative MRI of placental R2* (collaboration with Pediatrics and Ob/Gyn)

MRI-Guided Interventions

  • Real-time non-Cartesian MRI
  • Real-time MR temperature mapping
  • MRI-guided targeted biopsy and focal ablation
  • Artificial intelligence for procedural guidance
  • MRI-compatible robotic systems (collaboration with Tsao lab in Mechanical Engineering)
  • Precision MRI-guided nano-theranostics (collaboration with Zink lab in Chemistry)

News

Meet Our Team

Principal Investigator

holden_wu

Holden Wu, PhD

Professor of Radiology, Bioengineering, and Physics & Biology in Medicine

Current Members

Past Members

  • Ryan Andosca, MS (Lab rotation, Spring 2022)
  • Alexandra Artura, BS (Undergraduate student, 2021-2022)
  • Benjamin Azul, BS (Staff research associate, 2018-2019)
  • Tongxin Chen (Visiting undergraduate student, Summer 2016)
  • Chang Gao, BS (Lab rotation, Fall 2017)
  • Justin Kaufman (Undergraduate student, 2022-2023)
  • Tristan Kelly, BS (Undergraduate student, 2021-2023)
  • Kelsey Kuwahara, BS (Undergraduate student, 2020-2022)
  • Michael Lauria, BS (Lab rotation, Fall 2017)
  • Hannah Parish, BS (Medical student, 2021-2022)
  • Matthew Quesada (undergraduate student, Fall 2014)
  • Arash Safavi, MS (Staff research associate, 2017-2018)
  • Chengyang Song, BS (Visiting graduate student, Fall 2015)
  • Jacob Story, BS (Medical student, 2020-2022)
  • M. Wasil Wahi-Anwar, BS (Graduate student, 2014)
  • Yu Wang (Visiting undergraduate student, Summer 2017)
  • Cass Wong, BS (Undergraduate student, 2017)
  • Jiaqi Zhou (Remote undergraduate student, Summer 2022)