Group photo of the Wu lab

About

Our lab's research is focused on the development and translation of new technologies for Quantitative MRI-Guided Therapy, which includes detection/characterization, treatment planning, interventional guidance, and treatment monitoring of cancer and metabolic diseases.

Research Directions and Specific Projects

Quantitative Prostate MRI

  • Quantitative T2 and ADC mapping in prostate cancer
  • High-resolution diffusion-weighted MRI
  • Microstructural MRI
  • Integrated diagnostics for prostate cancer (collaboration with Urology and Pathology)

Quantitative Liver and Abdominal MRI

  • Free-breathing quantitative MRI of liver fat fraction and R2*
  • MRI and MRE of pediatric liver disease (collaboration with Pediatrics)
  • Artificial intelligence for body composition analysis

Quantitative Placenta MRI

  • Free-breathing quantitative MRI of placental R2* (collaboration with Pediatrics and Ob/Gyn)

MRI-Guided Interventions

  • Real-time non-Cartesian MRI
  • Real-time MR temperature mapping
  • MRI-guided targeted biopsy and focal ablation
  • Artificial intelligence for procedural guidance
  • MRI-compatible robotic systems (collaboration with MAC lab)
  • Precision MRI-guided nano-theranostics (collaboration with Zink lab

News

Meet Our Team

Principal Investigator

Headshot of Holden Wu, PhD.

Holden Wu, PhD

Professor of Radiology, Bioengineering, and Biomedical Physics IDP

Project Scientists

Graduate Students

Administrative Staff

Alumni

  • Tess Armstrong, PhD (PhD student and postdoc, 2013-2019; subsequently at ViewRay)
  • Isabel Dregely, PhD (Postdoc, 2013-2015; subsequently at King's College London)
  • Novena Rangwala, PhD (Postdoc, 2013-2016, jointly advised with Dr. Kyung Sung; subsequently at GE Healthcare)
  • Samantha Mikaiel, MS. (Graduate student, 2014-2018; subsequently at Vanguard)
  • Xinzhou Li, PhD (PhD student and postdoc, 2015-2022; subsequently at Siemens Healthineers)
  • Le Zhang, PhD (Postdoc, 2017-2020, subsequently at Mayo Clinic)
  • Nyasha Maforo, PhD (PhD student, 2018-2022, jointly advised with Dr. Dan Ennis; subsequently at University of Pennsylvania)
  • Zhaohuan Zhang, PhD (PhD student, 2016-2023)
  • Ashmita Deb, MS (Graduate student, 2022-2023; subsequently at Cleveland Clinic)
  • Sevgi Kafali, PhD (PhD student, 2018-2024; subsequently at Technical University Munich)
  • M. Wasil Wahi-Anwar, BS (Graduate student, 2014)
  • Matthew Quesada (undergraduate student, Fall 2014)
  • Chengyang Song, BS (Visiting graduate student, Fall 2015)
  • Tongxin Chen (Visiting undergraduate student, Summer 2016)
  • Yu Wang (Visiting undergraduate student, Summer 2017)
  • Cass Wong, BS (Undergraduate student, 2017)
  • Michael Lauria, BS (Lab rotation, Fall 2017)
  • Chang Gao, BS (Lab rotation, Fall 2017)
  • Arash Safavi, MS (Staff research associate, 2017-2018)
  • Benjamin Azul, BS (Staff research associate, 2018-2019)
  • Jacob Story, BS (Medical student, 2020-2022)
  • Kelsey Kuwahara, BS (Undergraduate student, 2020-2022)
  • Hannah Parish, BS (Medical student, 2021-2022)
  • Alexandra Artura, BS (Undergraduate student, 2021-2022)
  • Tristan Kelly, BS (Undergraduate student, 2021-2023)
  • Ryan Andosca, MS (Lab rotation, Spring 2022)
  • Jiaqi Zhou (Remote undergraduate student, Summer 2022)
  • Justin Kaufman (Undergraduate student, 2022-2023)

We are looking for new postdocs and graduate students!