Wu Lab
About
Our lab's research is focused on the development and translation of new technologies for Quantitative MRI-Guided Therapy, which includes detection/characterization, treatment planning, interventional guidance, and treatment monitoring of cancer and metabolic diseases.
Research Directions and Specific Projects
Quantitative Prostate MRI
- Quantitative T2 and ADC mapping in prostate cancer
- High-resolution diffusion-weighted MRI
- Microstructural MRI
- Integrated diagnostics for prostate cancer (collaboration with Urology and Pathology)
Quantitative Liver and Abdominal MRI
- Free-breathing quantitative MRI of liver fat fraction and R2*
- MRI and MRE of pediatric liver disease (collaboration with Pediatrics)
- Artificial intelligence for body composition analysis
Quantitative Placenta MRI
- Free-breathing quantitative MRI of placental R2* (collaboration with Pediatrics and Ob/Gyn)
MRI-Guided Interventions
- Real-time non-Cartesian MRI
- Real-time MR temperature mapping
- MRI-guided targeted biopsy and focal ablation
- Artificial intelligence for procedural guidance
- MRI-compatible robotic systems (collaboration with Tsao lab in Mechanical Engineering)
- Precision MRI-guided nano-theranostics (collaboration with Zink lab in Chemistry)
News
- National Cancer Institute Award - UCLA Newsroom | The Cancer Letter
- UCLA Innovation Fund Therapeutics Award - UCLA Newsroom
Meet Our Team
Principal Investigator
Holden Wu, PhD
Professor of Radiology, Bioengineering, and Physics & Biology in Medicine
Current Members
Shu-Fu Shih, PhD
Assistant Project Scientist
Qing Dai, PhD
Postdoctoral Scholar
Elif Aygun
Graduate Student Researcher
Timoteo Delgado-Esbenshade
Graduate Student Researcher
Wenwen Zhang
Graduate Student Researcher
Wenqi Zhou
Graduate Student Researcher
Christina (Nina) Kerr
Undergraduate Student
Heather Wilbur, MFA
Faculty Administrative Support
Past Members
Tess Armstrong, PhD
Alumni
Ashmita Deb, MS
Alumni
Isabel Dregely, PhD
Alumni
Sevgi Gokce Kafali, PhD
Alumni
Xinzhou Li, PhD
Alumni
Nyasha Maforo, PhD
Alumni
Samantha Mikaiel, MS
Alumni
Novena Rangwala, PhD
Alumni
Le Zhang, PhD
Alumni
Zhaohuan Zhang, PhD
Alumni
- Ryan Andosca, MS (Lab rotation, Spring 2022)
- Alexandra Artura, BS (Undergraduate student, 2021-2022)
- Benjamin Azul, BS (Staff research associate, 2018-2019)
- Tongxin Chen (Visiting undergraduate student, Summer 2016)
- Chang Gao, BS (Lab rotation, Fall 2017)
- Irene Hwang (Undergraduate student, 2025-2026)
- Justin Kaufman (Undergraduate student, 2022-2023)
- Tristan Kelly, BS (Undergraduate student, 2021-2023)
- Kelsey Kuwahara, BS (Undergraduate student, 2020-2022)
- Michael Lauria, BS (Lab rotation, Fall 2017)
- Hannah Parish, BS (Medical student, 2021-2022)
- Matthew Quesada (undergraduate student, Fall 2014)
- Arash Safavi, MS (Staff research associate, 2017-2018)
- Chengyang Song, BS (Visiting graduate student, Fall 2015)
- Jacob Story, BS (Medical student, 2020-2022)
- M. Wasil Wahi-Anwar, BS (Graduate student, 2014)
- Yu Wang (Visiting undergraduate student, Summer 2017)
- Riley Wheeler (Undergraduate student, 2026)
- Cass Wong, BS (Undergraduate student, 2017)
- Jiaqi Zhou (Remote undergraduate student, Summer 2022)